Science

Scientists discover a hidden driver of high cholesterol and a way to stop it

Scientists have uncovered a hidden mechanism that allows high-cholesterol diets to undermine the body's natural cholesterol defenses, and blocking it dramatically lowered harmful LDL cholesterol in mice.

✦ Extractive summary — built from the sources' own reporting•From 1 source•1 min read•Updated November 1, 2026, 1:57 AM UTC

Even more promising, an experimental drug targeting this pathway has already passed an early human safety trial, potentially speeding the development of a new treatment for high cholesterol.

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