• Citadel's Ken Griffin is skeptical of Elon Musk's ability to cut trillions from the federal budget.
• Tesla CEO Musk has been tapped to run the proposed Department of Government Efficiency by Trump.
• Entitlement reform would be needed for the level of cuts Musk has called for, Griffin said Wednesday.

Billionaire Citadel founder Ken Griffin wants to get America's "fiscal house in order" but doesn't believe Elon Musk can do it alone.

Speaking at Wednesday's DealBook conference in New York, Griffin said it's unlikely that Musk, who has become a close advisor of President-elect Donald Trump and is set to co-run the proposed Department of Government Efficiency or DOGE, will be able to cut the trillions he has called for without entitlement reform.

"Making cuts in any form or fashion will be very politically unpopular," said Griffin, who was one of the biggest donors to the Republican Party this election but declined to support Trump directly — though he said he voted for the real estate mogul.

Griffin — who paused for a couple of seconds when asked for his opinion about Musk's new task running Doge, prompting scattered laughs from a crowd that included fellow hedge-fund billionaire Dan Loeb and Polymarket founder Shayne Coplan — said the bond market could eventually become unsteady if there isn't a clean-up of the country's spending.

"To make Elon wear the entire burden of that responsibility is preposterous," he said.

Griffin, who lauded Musk's entrepreneurial abilities, also said he hopes the Federal Reserve will remain independent so it can make decisions too unpopular — but necessary — for politicians.

The wide-ranging interview between Griffin and New York Times editor and CNBC host Andrew Ross Sorkin revealed that the billionaire hedge-fund manager does not think Trump's most explosive economic policies, such as his aggressive tariff proposals, will go into effect.

Last week, Trump posted about implementing tariffs on countries like Brazil and Russia that were considering creating a new currency to reduce the power of the US dollar. "It's not going to happen," he said, bluntly about Trump's recent warning.

Griffin said this is how negotiating is done in real estate, and he believes items like tariffs are a "second-order" issue.

"America is open for business," Griffin said repeatedly, and he pushed that throughout the interview. Gone, he said, is the "paralyzing regulation" of Joe Biden's administration, and executives are "smiling from ear-to-ear."

"For corporate America, it's a better world today than it was before the election," he said.

Griffin's $65 billion firm had a strong November, returning 1.8% in its flagship Wellington fund. Asked if there was still room in the investment industry for smaller funds and individual investors, Griffin said there's always going to be a dominant incumbent in any industry.

"When I started out, I had to go compete with Salomon Brothers and Goldman Sachs," he said.

Now, new launches compete with his firm and peers like Millennium and Point72.

"Your entrepreneurs find a way to make it happen," he said.