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Yesterday — 20 January 2025Main stream

Trump orders US withdrawal from the World Health Organization

By: Beth Mole
20 January 2025 at 19:35

On his first day in office, President Trump issued an executive order to withdraw the US from the World Health Organization, a process that requires a one-year notice period as set out in a 1948 Joint Resolution of Congress.

Trump initially tried to extract the US from the United Nations health agency in July 2020, but the process did not come to completion before he was voted out of office.

At the time, Trump criticized the agency's handling of the COVID-19 pandemic, claimed it was protecting China, and asserted that it was overcharging the US in dues. "China has total control over the World Health Organization despite only paying $40 million per year, compared to what the United States has been paying, which is approximately $450 million a year," Trump said in 2020 prior to issuing the first notice of withdrawal.

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DC-area veterinarians on heightened alert amid potential inauguration risks

By: Beth Mole
20 January 2025 at 11:57

Veterinarians in the Washington, DC region have been put on alert for any unusual illnesses in their non-human patients amid today's presidential inauguration—a nod to the significance of potential zoonotic bioterror threats.

In a recent letter to Virginia veterinarians, the state health department requested assistance in the "enhanced surveillance," while noting that, currently, there is no report of threats or bioterrorism-related illnesses.

"As with any large-scale public event, there will be heightened security, and the region will be on alert or signs of bioterrorism or other potential threats," the letter read. "Enhanced surveillance is being conducted out of an abundance of caution."

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Anthony Fauci granted preemptive pardon in the last hours of Biden’s term

By: Beth Mole
20 January 2025 at 06:36

With just hours left in office, President Joe Biden has issued a preemptive pardon for Anthony Fauci, America's top infectious disease expert.

For nearly four decades, Fauci directed the National Institute of Allergy and Infectious Diseases. He advised seven presidents, beginning with Ronald Reagan and, among his many accomplishments, played a crucial role in the response to the HIV/AIDS epidemic. Fauci was a leading architect of PEPFAR, the global AIDS response program begun by President George W. Bush that is estimated to have saved 25 million lives. Fauci served as Biden's medical advisor until his retirement at the end of 2022.

"For more than half a century, Dr. Fauci served our country," Biden said in a statement released this morning. "He saved countless lives by managing the government’s response to pressing health crises, including HIV/AIDS, as well as the Ebola and Zika viruses. During his tenure as my Chief Medical Advisor, he helped the country tackle a once-in-a-century pandemic. The United States is safer and healthier because of him."

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Before yesterdayMain stream

Wegovy and Ozempic top list of 15 drugs up for next price negotiations

By: Beth Mole
17 January 2025 at 08:47

Blockbuster weight-loss and diabetes drugs Wegovy and Ozempic top the list of 15 drugs selected for the second round of federal price negotiations, which are scheduled to begin this year, with resulting bargained prices going into effect in 2027.

The first round of negotiations, involving 10 high-cost drugs, wrapped up in August, with resulting prices being 38 percent to 79 percent lower than list prices. Those negotiated prices will go into effect in 2026 and are expected to save people with Medicare prescription drug coverage $1.5 billion in out-of-pocket costs.

“Last year we proved that negotiating for lower drug prices works," Xavier Becerra, secretary of the Department of Health and Human Services (HHS), said in a statement. "Now we plan to build on that record by negotiating for lower prices for 15 additional important drugs for seniors."

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More cancer, less death? New alcohol-risk reviews offer conflicting takeaways

By: Beth Mole
17 January 2025 at 04:30

Heavy drinking is clearly bad for your health. But it's long been questioned whether moderate drinking is also risky—and, if so, how risky, exactly.

Health researchers have consistently found links between alcohol consumption and several types of cancers (namely mouth, throat, colon, rectal, liver, and breast), as well as liver diseases, injuries, and traffic accidents. But nailing down the health risks from the lower levels of drinking has been tricky. For one, much of the data on moderate drinking is from observational studies in different countries, cultures, and populations. They cannot determine if alcohol is the direct cause of any given association, and they may be swayed by other lifestyle factors. The resulting data can be noisy and inconsistent.

Moreover, many studies rely on people to self-report whether they drink and, if so, how much, which is problematic because people may not accurately assess and/or report how much they actually drink. A related problem is that studies in the past often compared drinkers to people who said they didn't drink. But, the trouble is, non-drinking groups are often some mix of people who are lifelong abstainers and people who used to drink but quit for some reason—maybe because of health effects. This latter group has the potential to have lingering health effects from their drinking days, which could skew any comparisons looking for health differences.

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Maker of weight-loss drugs to ask Trump to pause price negotiations: Report

By: Beth Mole
14 January 2025 at 14:26

Eli Lilly and other drugmakers are reportedly planning to urge the Trump administration to pause Medicare drug-price negotiations that were put in place by the Biden administration's Inflation Reduction Act (IRA).

"They need to fix [the IRA]," Eli Lilly CEO Dave Ricks told Bloomberg at the JPMorgan Healthcare Conference in San Francisco.

The results of the first round of IRA negotiations, announced in August, saw the list prices of 10 high-cost drugs get slashed by as much as 79 percent. Collectively, the negotiated prices are estimated to save seniors $1.5 billion in out-of-pocket costs in 2026, when the prices go into effect. The savings will likely be well received, given that KFF polling has found that over a quarter of Americans struggle to afford prescription medications, and 31 percent say they haven't taken medicines as prescribed due to costs.

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Biofilms, unwashed hands: FDA found violations at McDonald’s ex-onion supplier

By: Beth Mole
13 January 2025 at 15:44

The onion supplier behind a deadly E. coli outbreak linked to McDonald's Quarter Pounders this past fall had numerous health and sanitation violations, including employees with unwashed hands, dirty equipment, and puddles of Listeria bacteria. That's according to a Food and Drug Administration inspection report that was obtained by CBS News via a Freedom of Information Act request.

On October 22, the Centers for Disease Control and Prevention announced the outbreak investigation, which at that time had only been linked to 48 illnesses across 10 states, including one death. The slivered onions on the fast-food giant's popular Quarter Pounder burgers were an immediate suspect. McDonald's temporarily pulled the burgers from the menu in affected states, and the supplier of the suspect onions, Taylor Farms of Colorado, swiftly recalled thousands of cases. Ultimately, 104 were sickened across 14 states, with 34 people hospitalized and one dead.

On October 28, the FDA began a multi-day inspection of Taylor Farms' facility in Colorado Springs, in which inspectors found numerous violations. The facility processes "ready-to-eat" (RTE) produce, like the cut onions, that do not go through a lethal treatment step for any environmental pathogens before being sold to consumers. This makes any unsanitary conditions in the facility particularly risky for food safety.

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Public health emergency declared amid LA’s devastating wildfires

By: Beth Mole
10 January 2025 at 13:14

The US health department on Friday declared a public health emergency for California in response to devastating wildfires in the Los Angeles area that have so far killed 10 people and destroyed more than 10,000 structures.

As of Friday morning, 153,000 residents are under evacuation orders, and an additional 166,800 are under evacuation warnings, according to local reports.

Wildfires pose numerous health risks, including exposure to extreme heat, burns, harmful air pollution, and emotional distress.

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Man turns irreversibly gray from an unidentified silver exposure

By: Beth Mole
10 January 2025 at 10:47

When an 84-year-old man in Hong Kong was admitted to a hospital for a condition related to an enlarged prostate, doctors noticed something else about him—he was oddly gray, according to a case report in the New England Journal of Medicine.

His skin, particularly his face, had an ashen appearance. His fingernails and the whites of his eyes had become silvery. When doctors took a skin biopsy, they could see tiny, dark granules sitting in the fibers of his skin, in his blood vessels, in the membranes of his sweat glands, and in his hair follicles.

A blood test made clear what the problem was: the concentration of silver in his serum was 423 nmol/L, over 40 times the reference level for a normal result, which is less than 10 nmol/L. The man was diagnosed with a rare case of generalized argyria, a buildup of silver in the body's tissue that causes a blueish-gray discoloration—which is generally permanent.

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China is having standard flu season despite widespread HMPV fears

By: Beth Mole
8 January 2025 at 13:05

There's a good chance you've seen headlines about HMPV recently, with some touting "what you need to know" about the virus, aka human metapneumovirus. The answer is: not much.

It's a common, usually mild respiratory virus that circulates every year, blending into the throng of other seasonal respiratory illnesses that are often indistinguishable from one another. (The pack includes influenza virus, respiratory syncytial virus (RSV), adenovirus, parainfluenza virus, common human coronaviruses, bocavirus, rhinovirus, enteroviruses, and Mycoplasma pneumoniae, among others.) HMPV is in the same family of viruses as RSV.

As one viral disease epidemiologist at the US Centers for Disease Control summarized in 2016, it's usually "clinically indistinguishable" from other bog-standard respiratory illnesses, like seasonal flu, that cause cough, fever, and nasal congestion. For most, the infection is crummy but not worth a visit to a doctor. As such, testing for it is limited. But, like other common respiratory infections, it can be dangerous for children under age 5, older adults, and those with compromised immune systems. It was first identified in 2001, but it has likely been circulating since at least 1958.

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As US marks first H5N1 bird flu death, WHO and CDC say risk remains low

By: Beth Mole
7 January 2025 at 15:14

The H5N1 bird flu situation in the US seems more fraught than ever this week as the virus continues to spread swiftly in dairy cattle and birds while sporadically jumping to humans.

On Monday, officials in Louisiana announced that the person who had developed the country's first severe H5N1 infection had died of the infection, marking the country's first H5N1 death. Meanwhile, with no signs of H5N1 slowing, seasonal flu is skyrocketing, raising anxiety that the different flu viruses could mingle, swap genetic elements, and generate a yet more dangerous virus strain.

But, despite the seemingly fever-pitch of viral activity and fears, a representative for the World Health Organization today noted that risk to the general population remains low—as long as one critical factor remains absent: person-to-person spread.

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Controversial fluoride analysis published after years of failed reviews

By: Beth Mole
6 January 2025 at 16:07

Federal toxicology researchers on Monday finally published a long-controversial analysis that claims to find a link between high levels of fluoride exposure and slightly lower IQs in children living in areas outside the US, mostly in China and India. As expected, it immediately drew yet more controversy.

The study, published in JAMA Pediatrics, is a meta-analysis, a type of study that combines data from many different studies—in this case, mostly low-quality studies—to come up with new results. None of the data included in the analysis is from the US, and the fluoride levels examined are at least double the level recommended for municipal water in the US. In some places in the world, fluoride is naturally present in water, such as parts of China, and can reach concentrations several-fold higher than fluoridated water in the US.

The authors of the analysis are researchers at the National Toxicology Program at the National Institute of Environmental Health Sciences. For context, this is the same federal research program that published a dubious analysis in 2016 suggesting that cell phones cause cancer in rats. The study underwent a suspicious peer-review process and contained questionable methods and statistics.

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Flu surges in Louisiana as health department barred from promoting flu shots

By: Beth Mole
23 December 2024 at 09:35

Flu season is ramping up across the US, but Louisiana—the state that has reportedly barred its health department from promoting flu shots, as well as COVID-19 and mpox vaccines—is leading the country with an early and strong surge.

Louisiana's flu activity has reached the "Very High" category set by the Centers for Disease Control and Prevention, according to the latest data. The 13-category scale is based on the percentage of doctor's visits that were for influenza-like illnesses (ILIs) in the previous week. Louisiana is at the first of three "Very High" levels. Oregon is the only other state to have reached this level. The rest of the country spans the scale, with 13 jurisdictions at "High," including New York City and Washington, DC. There are 11 at "Moderate," 10 at "Low," and 19 at "Minimal."

Map of ILI activity by state Credit: CDC

Last week, NPR, KFF Health News, and New Orleans Public Radio WWNO reported that the state had forbidden the health department and its workers from promoting annual flu shots, as well as vaccines for COVID-19 and mpox. The policy was explicitly kept quiet and officials have avoided putting it in writing.

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Louisiana bars health dept. from promoting flu, COVID, mpox vaccines: Report

By: Beth Mole
20 December 2024 at 07:58

Louisiana's health department has been barred from advertising or promoting vaccines for flu, COVID-19, and mpox, according to reporting by NPR, KFF Health News, and New Orleans Public Radio WWNO.

Their investigative report—based on interviews with multiple health department employees who spoke on the condition of anonymity for fear of retaliation—revealed that employees were told of the startling policy change in meetings in October and November and that the policy would be implemented quietly and not put into writing.

Ars Technica has contacted the health department for comment and will update this post with any new information.

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Journal that published faulty black plastic study removed from science index

By: Beth Mole
19 December 2024 at 09:36

The publisher of a high-profile, now-corrected study on black plastics has been removed from a critical index of academic journals after failing to meet quality criteria, according to a report by Retraction Watch.

On December 16, Clarivate—a scholarly publication analytics company—removed the journal Chemosphere from its platform, the Web of Science, which is a key index for academic journals. The indexing platform tracks citations and calculates journal "impact factors," a proxy for relevance in its field. It's a critical metric not only for the journals but for the academic authors of the journal's articles, who use the score in their pursuit of promotions and research funding.

To be included in the Web of Science, Clarivate requires journals to follow editorial quality criteria. In an email to Ars Technica, Clarivate confirmed that Chemosphere was removed for "not meeting one or more of the quality criteria." According to Retraction Watch, Chemosphere has retracted eight articles this month and published 60 expressions of concern since April.

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Louisiana resident in critical condition with H5N1 bird flu

By: Beth Mole
18 December 2024 at 13:41

The Louisiana resident infected with H5N1 bird flu is hospitalized in critical condition and suffering from severe respiratory symptoms, the Louisiana health department revealed Wednesday.

The health department had reported the presumptive positive case on Friday and noted the person was hospitalized, as Ars reported. But a spokesperson had, at the time, declined to provide Ars with the patient's condition or further details, citing patient confidentiality and an ongoing public health investigation.

This morning, the Centers for Disease Control and Prevention announced that it had confirmed the state's H5N1 testing and determined that the case "marks the first instance of severe illness linked to the virus in the United States."

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“Unprecedented” decline in teen drug use continues, surprising experts

By: Beth Mole
17 December 2024 at 14:15

Teen drug use continued to fall in 2024, extending a dramatic decline spurred by the COVID-19 pandemic that experts expected would reverse now that the acute phase of the global crisis is well over.

But, according to data released Tuesday, the number of eighth, 10th, and 12th graders who collectively abstained from the use of alcohol, marijuana, or nicotine hit a new high this year. Use of illicit drugs also fell on the whole and use of non-heroin narcotics (Vicodin, OxyContin, Percocet) hit an all-time low.

"Many experts in the field had anticipated that drug use would resurge as the pandemic receded and social distancing restrictions were lifted," Richard Miech, team lead of the Monitoring the Future survey at the University of Michigan, said in a statement. "As it turns out, the declines have not only lasted but have dropped further."

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Huge math error corrected in black plastic study; authors say it doesn’t matter

By: Beth Mole
16 December 2024 at 14:23

Editors of the environmental chemistry journal Chemosphere have posted an eye-catching correction to a study reporting toxic flame retardants from electronics wind up in some household products made of black plastic, including kitchen utensils. The study sparked a flurry of media reports a few weeks ago that urgently implored people to ditch their kitchen spatulas and spoons. Wirecutter even offered a buying guide for what to replace them with.

The correction, posted Sunday, will likely take some heat off the beleaguered utensils. The authors made a math error that put the estimated risk from kitchen utensils off by an order of magnitude.

Specifically, the authors estimated that if a kitchen utensil contained middling levels of a key toxic flame retardant (BDE-209), the utensil would transfer 34,700 nanograms of the contaminant a day based on regular use while cooking and serving hot food. The authors then compared that estimate to a reference level of BDE-209 considered safe by the Environmental Protection Agency. The EPA's safe level is 7,000 ng—per kilogram of body weight—per day, and the authors used 60 kg as the adult weight (about 132 pounds) for their estimate. So, the safe EPA limit would be 7,000 multiplied by 60, yielding 420,000 ng per day. That's 12 times more than the estimated exposure of 34,700 ng per day.

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Bird flu jumps from birds to human in Louisiana; patient hospitalized

By: Beth Mole
13 December 2024 at 14:28

A person in Louisiana is hospitalized with H5N1 bird flu after having contact with sick and dying birds suspected of carrying the virus, state health officials announced Friday.

It is the first human H5N1 case detected in Louisiana. For now, the case is considered a "presumptive" positive until testing is confirmed by the Centers for Disease Control and Prevention. Health officials say that the risk to the public is low but caution people to stay away from any sick or dead birds. A spokesperson for Louisiana's health department told Ars that the hospitalized patient had contact with both backyard and wild birds.

Although the person has been hospitalized, their condition was not reported. The spokesperson said the department would not comment on the patient's condition due to patient confidentiality and an ongoing public health investigation.

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