Romano shares his four kids — daughter Alexandra, twin sons Matthew and Gregory as well as son Joseph — with his wife of 37 years, Anna

"It was a cool feeling," Romano tells PEOPLE. "We weren't admitting to ourselves, 'I'm a big sitcom star, and you're a big sitcom star,' but we understood this is kind of unique and cool"

The actor's daughter Ally, 34, got married in October, while his son Matthew, 31, was married in April

The actor is dad to daughter Alexandra, 34, and sons Matthew and Gregory, 31, and Joseph, 26

The 'Friends' alum also told PEOPLE that she "fantasized" about working with Romano before starring in Netflix's 'No Good Deed'

"It was fun," the Emmy winner told PEOPLE. "I'll do it again."

The pair star as a couple in search of a new home in the new Netflix comedy-thriller

The actor shares daughter Alexandra, 34, and sons Matthew and Gregory, 31, and Joseph, 26, with wife Anna

The actor and his wife share daughter Alexandra, 34, and sons Matthew and Gregory, 31, and Joseph, 26